Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.

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Section I - General Principles and Therapeutic Targets

Chapter 1: The Eye as Drug Target: Overview

Chapter 2: Drug Delivery Systems in Ophthalmic Applications

Chapter 3: IOP as a Target - Inflow and Outflow Pathways

Chapter 4: The ciliary body: a potential multifaceted functional neuroendocrine unit.

Chapter 5: Growth Factors and Neurotrophic Factors as Targets

Section II. Visual Pathway

Chapter 6: New therapies for Dry Eye Disease

Chapter 7: Refractive Surgery: Corneal Opacity (haze) after Surface Ablation

Chapter 8: Progress in Preventing Age-Related Cataract

Chapter 9: Myopia Pharmacology: Etiologic Clues, Therapeutic Potential

Section III. Inflammation, Immune System and Anti-infectives

Chapter 10: Immune system and the eye

Chapter 11: Ocular Allergy: Clinical, Therapeutic and Drug Discovery Considerations

Chapter 12: Ocular Inflammation in Anterior Segment

Chapter 13: Posterior Segment uveitis

Chapter 14: New Anti-Infectives for Ophthalmology

Section IV. Clinical Therapeutics

Chapter 15: Tissue Repair and Regeneration

Chapter 16: Therapeutic Drugs for Anterior Segment Ocular Surgery

Chapter 17: Therapeutic Drugs for Posterior Segment Vitrectomy Surgery

Chapter 18: Progress and Prospects in Ocular Gene Therapy

Section V. Retinal Diseases and Neuropathies

Chapter 19: Neuroprotection in Glaucoma

Chapter 20: Degenerative Retinopathies

Chapter 22: Ocular Angiogenesis